Reconstructed Human Epidermis (RHE)

ZenBio, has developed a cost-effective Reconstructed Human Epidermis (RHE) model which mimics the barrier function of human stratum corneum, as well as a complete viable epidermis. The ZenSkin Reconstructed Human Epidermis consists of normal human keratinocytes on a polycarbonate filter, in a chemically defined medium. Ideally suited for assessing the pre-clinical and R&D effects of topical compounds on human skin.

Applications include:

• Effects of UVA / UVB radiation
• Permeability assays
• Gene expression
• Differentiation
• Corrosion and irritation