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Life Technologies (India) Pvt Ltd. 306, Agarwal City Mall, opposite M2K Pitampura, Delhi-110034 (India) Tel # +91-11-4220-8000; 4220-8111; 4220-8222 Fax# +91-11-4220-8444, Mobile# +91-98105-21400 Email# customerservice@lifetechindia.com |
Neurotoxicity
Life Technologies is a leading company with a specialized toxicology program that focuses on a wide range of products, including pharmaceuticals, biopharmaceuticals, biologics, and chemicals. Their goal is to conduct thorough testing and analysis of these products, comparing the test results with a regulated historical database. To carry out these evaluations, Life Technologies employs a team of highly skilled technical personnel and qualified scientists who specialize in the field of neurotoxicology. Their expertise enables them to identify and assess any potential on or off-target effects of the tested substances. They also pay close attention to target tissue delivery, conducting comprehensive investigative studies.
In Vitro Assays for Neurotoxicity
- Developmental neurotoxicity
- Neurite outgrowth
- Synaptogenesis assay
Neurotoxicity Assays
- Neurobehavioral assays assess locomotion, learning, memory, startle, and observational behavior.
- Assessing abuse liability for all drugs crossing the blood-brain barrier.
- GLP-compliant ototoxicity testing measures auditory function, cytocochleogram, histology, and potential recovery.
- Neurochemistry analysis measures cholinesterase and neurotransmitter levels in various samples.
- Neuropathology analysis includes perfusion, morphometry, stereology, and qualitative evaluations.
Assessment of Neurotoxicity
- Acute neurotoxicity
- Sub chronic neurotoxicity
- Developmental neurotoxicity
- Behavioral and developmental toxicity
- Safety pharmacology
- NMDA receptor antagonist