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Life Technologies (India) Pvt Ltd. 306, Agarwal City Mall, opposite M2K Pitampura, Delhi-110034 (India) Tel # +91-11-4220-8000; 4220-8111; 4220-8222 Fax# +91-11-4220-8444, Mobile# +91-98105-21400 Email# customerservice@lifetechindia.com |
Multiparametric Toxicity
Our lab and our distinguished team of experts that facilitate the procedure are committed to providing multiparametric toxicity evaluation services to our clients. At Life Technologies, we have long held the belief that tailoring to the specific requirements of the researcher will allow for better medication development and discovery, as well as the creation of alternative solutions and the provision of information for more study. We may combine the crucial toxicity tests or we could let you decide which ones are best for your study. Cardiotoxicity, hepatotoxicity, and neurotoxicity are a few of the often utilized toxicity tests. We undertake the procedure by gathering biological samples, testing them, and evaluating the outcomes. With the aid of our screening panel and the most recent technology, our team conducts multiplexed cell-based assays that include cytotoxicity in order to offer safer leads.
Life Technologies Multiparametric Toxicity Assessment Services
- increased likelihood of clinical hepatotoxicity prediction (sensitivity of 70% and specificity of 100%)
- Extended panel for testing the metabolic competency of rat primary hepatocytes and HepG2 replicating cells for the presence of toxicologically important endpoints.
- To explore and detect early and late-stage toxicities, different time points are used.
- Including data on Cmax that is actual or forecasted and can be used to correct exposure-related consequences
- To evaluate SAR sets and identify candidates with the lowest risk for continued development, common toxicity signatures can be used.
In Vitro Toxicity Solutions by Life Technologies
- IC50 determination
- Cell loss/death using fluorescent imaging
- Nuclear size and morphology using fluorescent imaging
- Cell membrane permeability using fluorescent imaging
We use more than 50 different cell lines of human origin for cytotoxicity testing for your research study.