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Life Technologies (India) Pvt Ltd. 306, Agarwal City Mall, opposite M2K Pitampura, Delhi-110034 (India) Tel # +91-11-4220-8000; 4220-8111; 4220-8222 Fax# +91-11-4220-8444, Mobile# +91-98105-21400 Email# customerservice@lifetechindia.com |
Immunology
Numerous areas of immunology research, such as inflammation and autoimmune illness, which are a part of the immune study, happen to be covered by immune drug discovery therapies. We do primary cell assays that allow us to understand the drug's effectiveness and mode of action at the cellular level. In vitro research is used by Life Technologies to cut expenses and shift attrition in the early phases. These testing techniques offer a chance to reduce the risk associated with the progression and eliminate the need for in vivo models.
Discovery Services
In-Vitro Immunology Assays for Drug Screening:
Determines mechanism of action, screen compounds, validate biomarkers, and provide predictive immunotoxicology using following assays:
- Fibroblast-like synoviocyte activation assay
- Chemotaxis assay: Monocytes
- Chemotaxis assay: Neutrophils
- Conventional Dendritic cells activation assay
- Plasmacytoid Dendritic cells activation assay
- Anti-inflammatory assays
- Immunomodulatory assays
Available Models
- THP1 cell lines
- Human and rodent Peripheral Blood Mononuclear cells
- Human and rodent T cells
- Human and rodent Neutrophils
- Human and rodent Dendritic Cells
- Human and rodent Macrophages
Clinical Immunology Assays
- Flow cytometry for PK/PD
- Flow cytometry for CD marker analysis of immune cells
- ELISpot, to evaluate cellular immune response
- Multiplex cytokine analyses
Techniques Used: Flow cytometry (cytokines inside and outside of cells), Confocal/fluorescence microscopy (multi-color immunofluorescence), ELISA (fluorimetry/colorimetry), RTqPCR, and Western blotting.