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Life Technologies (India) Pvt Ltd. 306, Agarwal City Mall, opposite M2K Pitampura, Delhi-110034 (India) Tel # +91-11-4220-8000; 4220-8111; 4220-8222 Fax# +91-11-4220-8444, Mobile# +91-98105-21400 Email# customerservice@lifetechindia.com |
Genotoxicity
Toxicity testing is crucial and expensive when it comes to genotoxicity in many countries. The clinical advancement in the later phases is one of the many factors that contribute to rising costs. Contrarily, Life Technologies has made significant strides in genotoxicity testing to identify chemicals that may pose genotoxic hazards early in the drug discovery process. We provide packages for analyzing potential drugs at affordable prices. Our customers can select from a range of tests, buy certain gent tox assays, or combine different assays for in vitro toxicological services.
Vital Information Regarding Gene-Tox Assays:
- When conducting assays, we require a small amount of compound
- Rapid turnaround time
- AMES MPF assay using Xenometrix AG - ANIARA microplate kit method (OECD 471)
- CHO, CHL, A549, and human PBMCs are used in an in vitro micronucleus assay, along with cytotoxicity testing on a high content screening (HCS) platform (OECD 487).
- Assessment of cytotoxicity in an in vitro chromosomal aberration experiment employing the CHO cell line and human PBMCs (OECD 473)
- MLA (L5178YTk+/- cell line) and HPRT (CHO-K1 cell line) mutations are tested for in mammalian cells (OECD 490/476).
- In vitro comet assay using PBMC, CHO, CHL test systems on HCS platform
- A549, HepG2, and BEAS-2B cell lines are used in the H2AX double strand DNA damage response experiment on the HCS platform.