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Life Technologies (India) Pvt Ltd. 306, Agarwal City Mall, opposite M2K Pitampura, Delhi-110034 (India) Tel # +91-11-4220-8000; 4220-8111; 4220-8222 Fax# +91-11-4220-8444, Mobile# +91-98105-21400 Email# customerservice@lifetechindia.com |
Cardiovascular Disease
Cardiovascular diseases have reached epidemic proportions worldwide, posing a significant health challenge. In response to this pressing issue, we are dedicated to supporting researchers in their quest to find new treatments and solutions. Our organization is committed to promoting cardiovascular research by providing a range of specialized services and cutting-edge facilities that can facilitate and advance your R&D efforts.With a diverse array of disease models at our disposal, we offer customizable options to suit your specific study plans.
Discovery Services
- Cardioprotective studies
- Hypertrophic cardiomyopathy related studies
- Myocardial Infarction based studies
- Atrial fibrillation (AF) (cardiac arrhythmia) based studies
- hERG : Patch-clamp assay
- hERG serum shift assays
- Ion channel trafficking assay
- Action potential duration (ADP) assays
- Cardiac marker detection: Troponin I, II
- Integrated human cardiomyocyte assays
- Hit Identification
- High content imaging- analysis of drug interaction at the sub-cellular level
Available Models
We specialize in human primary cell-based assays, utilizing both 2D and 3D disease-relevant models. Our cutting-edge techniques allow for the accurate representation of human biology, enabling more reliable and translatable results.
3D Models
- 3D microtissue- Human mesenchymal stem cell-derived cardiomyocytes (hMSCs-CMs)
- Spheroids- induced pluripotent stem cell derived cardiomyocytes (iPSCs - CMs)
- Cardiac endothelial cells
- Cardiac fibroblasts
- Heart-on-Chip
2D Models
- hERG stably transfected HEK293 cells
- Human mesenchymal stem cell-derived cardiomyocytes (hMSCs-CMs)
- induced Pluripotent Stem Cell (iPSC) derived cardiomyocytes
- H9C2 cell line
Techniques Used
With our expertise in Electrophysiology, we can precisely measure and analyze electrical activity within cells, enabling the evaluation of drug effects on ion channels and membrane potentials. This information is crucial in understanding the impact of drugs on cellular excitability and signaling.