MDM2 Amplification Detection Assay: Precision Genomic Analysis for Cancer Research

MDM2 amplification detection assay

Technology	FISH	ISH
MDM2 amplification detection assay
Application	Gene amplification	Gene amplification
Area of interest	Formalin-fixed paraffin-embedded tissue sections or fixed cytological specimen	Formalin-fixed paraffin-embedded tissue sections or fixed cytological specimen
Region	12p11.1-q11.1 and 12q15	12p11.1-q11.1 and 12q15
Label	♦ (AF488, 2000) and ♦(AF555, 3000)	Biotin (0100) and Digoxigenin (9900)
Product No.	C817K.2030.05	C817K.0199.05
	C817K.2030.10	C817K.0199.10
Product Type	Research use only (RUO) or In vitro diagnostics (IVD)	Research use only (RUO)
Intended Use	The REMBRANDT® MDM2 amplification FISH detection assay is designed to target the MDM2 gene (12q14.3-15) compared to a CEP12 control probe which allows to detect amplifications of MDM2 and simultaneous enumeration of chromosome 12.	The REMBRANDT® MDM2 amplification ISH detection assay is designed to target the MDM2 gene (12q14.3-15) compared to a CEP12 control probe which allows to detect amplifications of MDM2 and simultaneous enumeration of chromosome 12.
Kit contents	C817P.2030 LSI 12q15/CEP12 FISH probe mix	C817P.0199 LSI 12q15/CEP12 ISH probe mix
	R018R.0000 Pepsin diluent	R025R.0000 PanWash 4 25x SSC
	R011R.0000 Pepsin powder	R018R.0000 Pepsin diluent
	R025R.0000 PanWash 4 (FISH) 25x SSC	R011R.0000 Pepsin powder
	R026R.000 Pre-treatment buffer	R026R.000 Pre-treatment buffer
	Z000R.0050 Fluorescent mounting medium

Catalog No.	MDM2 amplification detection assay

C817K.2030.05	REMBRANDT® MDM2 amplification FISH detection assay
C817K.2030.10	REMBRANDT® MDM2 amplification FISH detection assay
C817K.0199.05	REMBRANDT® LSI 12q15/CEP12 amplification ISH detection assay
C817K.0199.10	REMBRANDT® LSI 12q15/CEP12 amplification ISH detection assay

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