Sections of mouse liver, stained with monoclonal antibody F4/80 Normal liver with positive Kupffer cells
![img712](../images/img712.png)
Liver of a mouse, 2 days after injection with clodronate-liposomes. Kupffer cells have been depleted
![img713](../images/img713.png)
Sections of mouse spleen stained for acid phosphatase Normal spleen with positive splenic macrophages
![img714](../images/img714.png)
Spleen of a mouse 2 days after injection with clodronate liposomes. Only few macrophages are left
![img715](../images/img715.jpg)