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Natural Product-like Compound Library

Cat. No.: HY-L021L


Natural products are an attractive source with varied structures that exhibit potent biological activities, and desirable pharmacological profiles. The core scaffold of a natural product can also provide a biologically validated framework upon which to display diverse functional groups. Inspired by bioactive natural products, natural product-like compounds, occupying the same chemical space, are ideally suited to explore and to facilitate understanding of biological pathways.


MCE provides a unique collection of 521 natural product-like compounds that are structurally like Steroids, Tannins, Flavonoids, Quinones, Isoquinolines, etc. This library is an important source of lead compounds for drug discovery.


MCE Natural Product-like Compound Library can be supplied as pre-dissolved Solutions or Solid. For pre-dissolved solutions in this library, there are 503 compounds supplied in 10 mM solution, 16 compounds supplied in 2 mM solution and 2 compounds supplied in 3 mg/mL solution.


For pre-dissolved solutions, 10 mM for compounds with the solubility not lower than 10 mM, 2 mM for compounds with solubility between 2 mM and 10 mM, and 3 mg/mL for compounds with unconfirmed molecular weight and solubility not lower than 3 mg/mL.


Size (Pre-dissolved Solution or Solid)


  • 30 μL/well Solution
    (10 mM, 2 mM and 3 mg/mL Pre-dissolved Solution)
  • 50 μL/well Solution
    (10 mM, 2 mM and 3 mg/mL Pre-dissolved Solution)
  • 100 μL/well Solution
    (10 mM, 2 mM and 3 mg/mL Pre-dissolved Solution)
  • 2 × 100 μL/well Solution
    (10 mM, 2 mM and 3 mg/mL Pre-dissolved Solution)

Publications Citing Use of MCE Compound Libraries


Description & Advantages
• A unique collection of 521 natural products structurally like compounds for high throughput screening (HTS) and high content screening (HCS).
• The compounds in the library are structurally like Steroids, Tannins, Flavonoids, Quinones, Isoquinolines and so on.
• A useful tool for drug discovery as an important source of lead compounds.
• Structurally diverse, bioactive, and cell permeable.
• More detailed compound information with structure, IC50, and other chemical & biological data.
• NMR and HPLC validated ensure high purity.
• All compounds are in stock and continuously updated.
Product Details

• Formulation:A collection of 521 natural products structurally like compounds supplied as pre-dissolved Solutions or Solid
Solution: 503 compounds supplied in 10 mM solution, 16 compounds supplied in 2 mM solution, 2 compounds supplied in 3 mg/mL solution.


• Layout: 96-well storage tube or 96-well plate: 1st and 12th column are left empty.

384-well plate: the first two columns and the last two columns are left empty.

Compounds with different concentrations or dissolved in different solvents will be put on separate plates. This way of layout may increase the number of plates because there could be three solvents and three concentrations.

If you have other requirements, please let us know.


• Container:96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode


• Storage:-80°C


• Shipping:Blue ice
Composition
Natural Product-like Compound Library (Source: MedChem Express)

Documentation

Library Handling Instructions (351 KB)
Life Technologies (India) Pvt Ltd. 

306, Agarwal City Mall, opposite M2K Pitampura, Delhi-110034 (India)
Tel # +91-11-4220-8000; 4220-8111; 4220-8222 Fax# +91-11-4220-8444,
Mobile# +91-98105-21400
Email# customerservice@lifetechindia.com