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Life Technologies (India) Pvt Ltd. 306, Agarwal City Mall, opposite M2K Pitampura, Delhi-110034 (India) Tel # +91-11-4220-8000; 4220-8111; 4220-8222 Fax# +91-11-4220-8444, Mobile# +91-98105-21400, Toll Free# 1800-120-2434 Email# customerservice@lifetechindia.com |
FDA Approved Drug Library Mini
Cat. No.: HY-L022M
New drug development is a time-consuming and high-cost process. Drug repurposing (also called drug repositioning, reprofiling or re‑tasking) offers various advantages over developing an entirely new drug for a given indication. First, the risk of failure is lower. Second, the time frame for drug development can be reduced. Third, less investment is needed. Approved drugs have identified bioactivities, good pharmacokinetic characteristics and safety which are suitable for drug repurposing.
MCE owns a unique collection of 2710 approved compounds which have been completed extensive preclinical and clinical studies and have well-characterized bioactivities, safety and bioavailability properties. The package of this library is 96-well microplate with peelable foil seal, which makes the screening process easier and faster.
Size (Pre-dissolved Solution or Solid)
- 10 μL/well Solution
(10 mM , 2 mM and 3 mg/mL Pre-dissolved Solution)
Publications Citing Use of MCE Compound Libraries
• J Exp Med. 2023 Mar 6;220(3):e20221316. [Abstract]
• iScience. 5 January 2022, 103731.
• Molecules. 2022 May 16;27(10):3182. [Abstract]
• J Appl Microbiol. 2021 Nov 20. [Abstract]
• Clin Transl Oncol. 2022 Feb 3. [Abstract]
• BMC Bioinformatics. 2021 Jan 7;22(1):17. [Abstract]
• Assay Drug Dev Technol. 2021 Dec 13. [Abstract]
• bioRxiv. 2021 Jun 15;2021.05.15.444128. [Abstract]
• Research Square Print. 2022 Jul.
• University of Ottawa. Department of Cellular and Molecular Medicine. 2021 Feb 23.
• Nat Med. 2017 Apr 7;23(4):405-408. [Abstract]
• J Med Virol. 2021 Jun 1. [Abstract]
• Nat Commun. 2018 Apr 26;9(1):1677. [Abstract]
• Nat Commun. 2020 Sep 4;11(1):4417. [Abstract]
• Acta Pharm Sin B. 2021 Jan;11(1):143-155. [Abstract]
• EMBO Mol Med. 2021 Dec 20;e14608. [Abstract]
• J Biomed Sci. 2018 Aug 2;25(1):60. [Abstract]
• Cell Syst. 2018 Apr 25;6(4):424-443.e7. [Abstract]
• Cell Rep. 2017 Jul 25;20(4):999-1015. [Abstract]
• J Cheminform. 2018 Jul 31;10(1):34. [Abstract]
• J Med Chem. 2018 Jan 11;61(1):360-371. [Abstract]
• J Invest Dermatol. 2021 Sep 14;S0022-202X(21)01672-9. [Abstract]
• Life Sci. 2020 Oct 1;258:118228. [Abstract]
• Front Pharmacol. 2020 Nov 11;11:580407. [Abstract]
| Description & Advantages | |||||||||||||||||||
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• A unique collection of 2710 approved drugs for high throughput screening (HTS) and high content screening (HCS). • Used in the research of oncology, cardiology, anti-inflammatory, immunology, dermatology, endocrinology, neurology, and more. • A useful tool for researching new targets of marketed old drugs. • All compounds have been approved by the FDA, EMA and other countries. • Structurally diverse, bioactive, and cell permeable. • More detailed compound information with structure, IC50, and brief introduction. • NMR and HPLC validated ensure high purity. • All compounds are in stock and continuously updated.
• Easily peelable foil seal makes the screening process easier and faster. • Lower price, more compounds. • Avoid multiple and uneven dispensing. • Reduce risks of product cross-contamination. • Avoid reduced activity due to long-term storage. |
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| FAQ | ||||||
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1 Can we centrifuge the whole rack? Yes. It is advised to centrifuge all of the samples before experimental use. Recommended centrifugation for this plate is 1000g or less. 2 How can I use the 2D barcode on the microplate lid? Use an HD barcode scanner to scan the barcode, and then find the corresponding plate and compound information in the Excel or the provided hard copy. 3 What are the appropriate compound storage conditions? For solutions, store at -80°C. For some special compounds, specific handling instructions are provided. 4 After receiving the compound library, the ice box has melted, will this affect the efficacy of thecompound? MCE products are primarily chemical synthesis products which are not temperature sensitive. The ice boxes inside of the packages are used to prevent the occurrence of extreme temperatures during the process of transportation, and a melted icebox will not affect the reagent quality. After transit, the icebox is no longer needed.
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| Product Details | ||||||
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• Formulation:A collection of 2710 marketed drugs supplied as pre-dissolved Solutions • Layout: 96-well storage tube or 96-well plate: 1st and 12th column are left empty. 384-well plate: the first two columns and the last two columns are left empty. Compounds with different concentrations or dissolved in different solvents will be put on separate plates. This way of layout may increase the number of plates because there could be three solvents and three concentrations. If you have other requirements, please let us know. • Container:96-well Plate With Peelable Foil Seal • Storage:-80°C • Shipping:Blue ice |
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| Composition | ||||||
| Natural Product Library (Source: MedChem Express) | ||||||
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