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Bioactive_Compound_Library
Cat. No.: HY-L001
Bioactive compounds are a general term for a class of substances that can cause certain biological effects in the body, which are the main source of small molecule drugs. These compounds generally penetrate cell membranes, act on specific target proteins in cells, regulate intracellular signaling pathways, and cause some changes in cell phenotype.
MCE owns a unique collection of 17164 compounds with confirmed biological activities and clear targets. These compounds include natural products, innovative compounds, approved compounds, and clinical compounds. These can also be used for signal pathway research, drug discovery and drug repurposing, etc. MCE Bioactive Compound Library can be supplied as pre-dissolved Solutions or Solid. For pre-dissolved solutions in this library, there are 16759 compounds supplied in 10 mM solution, 328 compounds supplied in 2 mM solution and 77 compounds supplied in 3 mg/mL solution.
For pre-dissolved solutions, 10 mM for compounds with the solubility not lower than 10 mM, 2 mM for compounds with solubility between 2 mM and 10 mM, and 3 mg/mL for compounds with unconfirmed molecular weight and solubility not lower than 3 mg/mL.
Size (Pre-dissolved Solution or Solid)
- 50 μL/well Solution
(10 mM , 2 mM and 3 mg/mL Pre-dissolved Solution) - 100 μL/well Solution
(10 mM , 2 mM and 3 mg/mL Pre-dissolved Solution) - 2 × 100 μL/well Solution
(10 mM , 2 mM and 3 mg/mL Pre-dissolved Solution)
Publications Citing Use of MCE Compound Libraries
• Nature Metabolism. 2021 May;3(5):682-700. [Abstract]
• Protein Cell. 28 September 2022.
• Sep Purif Technol. 2018, 212:483-489.
• Cell Chem Biol. 2022 Aug 17;S2451-9456(22)00277-X. [Abstract]
• Eur J Med Chem. 2019 Feb 1;163:169-182. [Abstract]
• J Antibiot (Tokyo). 2019 Jul;72(7):545-554. [Abstract]
• Mem Inst Oswaldo Cruz. 2022 Mar 11;117:e210402. [Abstract]
• AfricArXiv Preprints. 2021 Jun.
• FASEB BioAdvances. 2021;00:1-22.
• Green Approaches in Medicinal Chemistry for Sustainable Drug Design. 2020, 779-818.
• Nat Med. 2017 Apr 7;23(4):405-408. [Abstract]
• Chem Rev. 2020 Oct 28;120(20):11616-11650. [Abstract]
• Circulation. 2022 Apr 12;145(15):1154-1168. [Abstract]
• J Med Virol. 2021 Jun 1. [Abstract]
• Nat Commun. 2018 Apr 26;9(1):1677. [Abstract]
• Nat Commun. 2020 Sep 4;11(1):4417. [Abstract]
• Acta Pharm Sin B. 2021 Jan;11(1):143-155. [Abstract]
• EMBO Mol Med. 2021 Dec 20;e14608. [Abstract]
• J Biomed Sci. 2018 Aug 2;25(1):60. [Abstract]
• Cell Syst. 2018 Apr 25;6(4):424-443.e7. [Abstract]
• Cell Rep. 2017 Jul 25;20(4):999-1015. [Abstract]
• J Cheminform. 2018 Jul 31;10(1):34. [Abstract]
• J Med Chem. 2018 Jan 11;61(1):360-371. [Abstract]
• J Invest Dermatol. 2021 Sep 14;S0022-202X(21)01672-9. [Abstract]
| Description & Advantages | ||||||
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• A unique collection of 17164 bioactive compounds including natural products, enzyme inhibitors, receptor ligands, and drugs for high throughput screening (HTS) and high content screening (HCS). • Bioactivity and safety confirmed by preclinical research and clinical trials. Some have been approved by FDA. • Widely used in the research focus areas such as Cancer, Stem Cell, Neuronal Signaling, Immunity, and more. • Structurally diverse, medicinally active, and cell permeable. • More detailed compound information with structure, IC50, and other chemical & biological data. • NMR and HPLC validated to ensure high purity and quality. • All compounds are in stock and continuously updated. |
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| Product Details | ||||||
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• Formulation:A collection of 17164 bioactive compounds supplied as pre-dissolved Solutions or Solid Solution: 16759 compounds supplied in 10 mM solution, 328 compounds supplied in 2 mM solution, 77 compounds supplied in 3 mg/mL solution. • Layout: 96-well storage tube or 96-well plate: 1st and 12th column are left empty. 384-well plate: the first two columns and the last two columns are left empty. Compounds with different concentrations or dissolved in different solvents will be put on separate plates. This way of layout may increase the number of plates because there could be three solvents and three concentrations. If you have other requirements, please let us know. • Container:96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode • Storage:-80°C • Shipping:Blue ice |
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| Composition | ||||||
| Bioactive Compound Library(Source: MedChem Express) | ||||||
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