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Anti-infection_Compound_Library
Cat. No.: HY-L002
An infection occurs when another organism enters a person’s body and causes disease. The organisms that cause infections are very diverse and can include things like viruses, bacteria, fungi, and parasites. The immune system is an effective barrier against infectious agents.
MCE provides a unique collection of 2515 anti-infective compounds with anti-bacterial, anti-viral, anti-fungal and anti-parasite activities that can be used for drug screening and other research in anti-microbial area.
MCE Anti-Infection Compound Library can be supplied as pre-dissolved Solutions or Solid. For pre-dissolved solutions in this library, there are 2428 compounds supplied in 10 mM solution, 63 compounds supplied in 2 mM solution and 24 compounds supplied in 3 mg/mL solution.
For pre-dissolved solutions, 10 mM for compounds with the solubility not lower than 10 mM, 2 mM for compounds with solubility between 2 mM and 10 mM, and 3 mg/mL for compounds with unconfirmed molecular weight and solubility not lower than 3 mg/mL.
Size (Pre-dissolved Solution or Solid)
- 30 μL/well Solution
(10 mM , 2 mM and 3 mg/mL Pre-dissolved Solution) - 50 μL/well Solution
(10 mM, 2 mM and 3 mg/mL Pre-dissolved Solution) - 100 μL/well Solution
(10 mM, 2 mM and 3 mg/mL Pre-dissolved Solution) - 2 × 100 μL/well Solution
(10 mM, 2 mM and 3 mg/mL Pre-dissolved Solution)
Publications Citing Use of MCE Compound Libraries
• J Med Chem. 2022 Aug 4. [Abstract]
• Acta Pharmacol Sin. 2021 Apr 27;1-11. [Abstract]
• Virol Sin. 2021 Jun;36(3):501-509. [Abstract]
• ACS Infect Dis. 2021 Aug 13;7(8):2390-2401. [Abstract]
• Research Square Print. 2022 Jul.
• Nat Med. 2017 Apr 7;23(4):405-408. [Abstract]
• Chem Rev. 2020 Oct 28;120(20):11616-11650. [Abstract]
• Circulation. 2022 Apr 12;145(15):1154-1168. [Abstract]
• J Med Virol. 2021 Jun 1. [Abstract]
• Nat Commun. 2018 Apr 26;9(1):1677. [Abstract]
• Nat Commun. 2020 Sep 4;11(1):4417. [Abstract]
• Acta Pharm Sin B. 2021 Jan;11(1):143-155. [Abstract]
• Cell Syst. 2018 Apr 25;6(4):424-443.e7. [Abstract]
• Cell Rep. 2017 Jul 25;20(4):999-1015. [Abstract]
• J Cheminform. 2018 Jul 31;10(1):34. [Abstract]
• J Med Chem. 2018 Jan 11;61(1):360-371. [Abstract]
• J Invest Dermatol. 2021 Sep 14;S0022-202X(21)01672-9. [Abstract]
• Life Sci. 2020 Oct 1;258:118228. [Abstract]
• Front Pharmacol. 2020 Nov 11;11:580407. [Abstract]
• Epigenetics Chromatin. 2020 Aug 3;13(1):31. [Abstract]
• Sci Rep. 2017 Oct 16;7(1):12881. [Abstract]
• ACS Chem Biol. 2016 Dec 16;11(12):3400-3411. [Abstract]
• ACS Chem Biol. 2016 May 20;11(5):1245-54. [Abstract]
• Biol Reprod. 2017 Nov 1;97(5):671-687. [Abstract]
• SLAS Discov. 2020 Sep;25(8):895-905. [Abstract]
• Biochem Biophys Res Commun. 2018 Sep 3;503(1):297-303. [Abstract]
| Description & Advantages | ||||||
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• A unique collection of 2515 bioactive anti-infection compounds for high throughput screening (HTS) and high content screening (HCS). • Targets such as Bacteria, Fungi, Parasite, CMV, HIV, SARS-CoV, Influenza Virus, etc. • Bioactivity and safety confirmed by preclinical research and clinical trials, some have been approved by FDA. • A useful tool to study infectious diseases or develop new anti-infection drugs. • Structurally diverse, medicinally active, and cell permeable. • More detailed compound information with structure, IC50, and other chemical & biological data. • NMR and HPLC validated to ensure high purity and quality. • All compounds are in stock and continuously updated. |
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| Product Details | ||||||
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• Formulation:A collection of 2515 bioactive anti-infection compounds supplied as pre-dissolved Solutions or Solid • Layout: 96-well storage tube or 96-well plate: 1st and 12th column are left empty. 384-well plate: the first two columns and the last two columns are left empty. Compounds with different concentrations or dissolved in different solvents will be put on separate plates. This way of layout may increase the number of plates because there could be three solvents and three concentrations. If you have other requirements, please let us know. • Container:96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode • Storage:-80°C • Shipping:Blue ice |
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| Composition | ||||||
| Anti-Infection Compound Library (Source: MedChem Express) | ||||||
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| Documentation | ||||||