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Alkaloids Library

Cat. No.: HY-L071


Alkaloids are a large and complex group of cyclic compounds that contain N. About 2,000 different alkaloids have been isolated. Important alkaloids include morphine, strychnine, atropine, colchicine, ephedrine, quinine, and nicotine. Alkaloids are useful as diet ingredients, supplements, and pharmaceuticals, in medicine and in other applications in human life. They showed anti-inflammatory, anticancer, analgesics, local anesthetic and pain relief, neuropharmacologic, antimicrobial, antifungal, and many other activities. Alkaloids are also important compounds in organic synthesis for searching new semisynthetic and synthetic compounds with possibly better biological activity than parent compounds.


MCE designs a unique collection of 449 alkaloids that all come from natural products. MCE Alkaloids Library is a useful tool for drug discovery that can be used for high throughput screening (HTS) and high content screening (HCS).


MCE Alkaloids Library  can be supplied as pre-dissolved Solutions or Solid. For pre-dissolved solutions in this library, there are 429 compounds supplied in 10 mM solution, 18 compounds supplied in 2 mM solution and 2 compounds supplied in 3 mg/mL solution.


For pre-dissolved solutions, 10 mM for compounds with the solubility not lower than 10 mM, 2 mM for compounds with solubility between 2 mM and 10 mM, and 3 mg/mL for compounds with unconfirmed molecular weight and solubility not lower than 3 mg/mL./p>

Size (Pre-dissolved Solution or Solid)


  • 30 μL/well Solution
    (10 mM , 2 mM and 3 mg/mL Pre-dissolved Solution)
  • 50 μL/well Solution
    (10 mM , 2 mM and 3 mg/mL Pre-dissolved Solution)
  • 100 μL/well Solution
    (10 mM , 2 mM and 3 mg/mL Pre-dissolved Solution)
  • 2 × 100 μL/well Solution
    (10 mM , 2 mM and 3 mg/mL Pre-dissolved Solution)

Publications Citing Use of MCE Compound Libraries


 

Description & Advantages

•   A unique collection of 449 alkaloids for high throughput screening (HTS) and high content screening (HCS).

•   The compounds in the library contain indoles, quinolines, isoquinolines, pyrrolidines, pyridines, pyrrolizidines, tropanes, and terpenoids and steroids.

•   A useful tool for drug discovery as an important source of lead compounds.

•   Bioactivity and safety confirmed by preclinical research and clinical trials. Some compounds have been approved by FDA.

•   Structurally diverse, bioactive, and cell permeable.

•   More detailed compound information with structure, IC50, and brief introduction.

•   NMR and HPLC validated ensure high purity.

•   All compounds are in stock and continuously updated.

Product Details

• Formulation:A collection of 449 bioactive Alkaloids supplied as pre-dissolved Solutions or Solid
Solution: 429 compounds supplied in 10 mM solution, 18 compounds supplied in 2 mM solution, 2 compounds supplied in 3 mg/mL solution.


• Layout: 96-well storage tube or 96-well plate: 1st and 12th column are left empty.

384-well plate: the first two columns and the last two columns are left empty.

Compounds with different concentrations or dissolved in different solvents will be put on separate plates. This way of layout may increase the number of plates because there could be three solvents and three concentrations.

If you have other requirements, please let us know.


• Container:96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode


• Storage:-80°C


• Shipping:Blue ice

Composition
Alkaloids Library (Source: MedChem Express)



Documentation
Life Technologies (India) Pvt Ltd. 

306, Agarwal City Mall, opposite M2K Pitampura, Delhi-110034 (India)
Tel # +91-11-4220-8000; 4220-8111; 4220-8222 Fax# +91-11-4220-8444,
Mobile# +91-98105-21400
Email# customerservice@lifetechindia.com