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Carbenicillin

  • Product ID: C346

Introduction:

Carbenicillin is a derivative of penicillin with a mode of action similar to benzylpenicillin. It is the most commonly used antibiotic for the elimination of Argobacterium tumefaciens during plant transformation.


C346 Carbenicillin, Disodium Salt


Synonym: a - Carboxybenzylpenicillin, Disodium Salt
CAS: 4800 - 94 - 6
Formula: C 17 H 16 N 2 O 6 SNa 2
Molecular Wt: 422.41


Properties

Properties
Form: Powder
Appearance: White to Cream Powder
Application: Plant Tissue Cultur e Antibiotic
Solubility: Water in Water
Typical Working Concentration: 2 to 6°C
Storage Temp: 2 to 8 °C
Storage Temp of Stock Solution: 2 to 8°C
Other Notes: Stock solution is stable for 24 hrs when stored at Room Temperature, 72 hrs at 2 - 6 o C and 12 months at - 20 o C (i.e. non - frost freezer)

Application Notes
Carbenicillin is a derivative of penicillin with a mode of action similar to benzylpenicillin. It is the most commonly used antibiotic for the elimination of Argobacterium tumefaciens due to its relatively low toxicity for a wide range of plant sp ecies . A concentration of 500 mg/ L is recommended to achieve microbe toxicity; however, concentration s up to 1000 mg/L have been reported in plant tissue culture literature.

Please Note: While Phyto Technology Laboratories® tests each lot of this product with two or more plant cell/ tissue culture lines, it is the sole responsibility of the purchaser to determine the appropriateness of this product for the specific plants that are being cultured and applications that are being used.

References
Merck 13, 1801

Sweetman SC (ed) (2007) , Martindale: The Complete Drug Reference 35. C hina: Pharmaceutical Press . Nauerby B, Billing K , and Wyndaele R. (1997) Influence of the antibiotic timentin on plant regeneration compared to carbenicillin and cefotaxime in concentr ations suitable for elimination of Agrobacterium tumefaciens . Plant Science Vol. 123(1 - 2) pg. 169 - 177.

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